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          Point
         2
          
         Intro
          
         
         Pathway 
         
          Deficits 
         
         Summary 
         
         Problems 
         
         
          
          
         
         Contents
          
         
         Anatomy
          
         
           
         
          
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           In gross terms a
         lesion of the anterolateral system will result in a
         deficit in pain, temperature and crude touch
         on the contralateral side of the body
         below the level of the lesion. That is, a lesion of
         the ALS in the upper cervical region results in a pain and
         temperature deficit of the entire contralateral side
         of the body. A lesion of the ALS in the upper thoracic cord
         will result in a deficit in pain and temperature from the
         thorax and lower extremities on the contralateral
         side because the fibers which are interrupted at this level
         convey pain and temperature information from these areas.
         The upper extremity is safe because the fibers
         conveying information regarding pain and temperature from
         this region are still reaching the thalamus (VPL) and in
         turn the cortex. These fibers lie in the anterolateral
         system ROSTRAL to the lesion and are not interrupted.
          
         
          The contralateral
         deficits in pain and temperature following a lesion of the
         ALS are more detectable than the deficit in crude
         touch. Why?? Because the dorsal column system is intact and
         it "covers" for the loss during the neurological exam. For
         example, following a lesion of the left ALS at C2
         there is a deficit in crude touch on the right
         (contra.) side but the dorsal columns are OK on the
         right. Of course, if you have a lesion of the dorsal
         columns only, you still have the crude touch being conveyed
         by the ALS. For example, following a lesion of the
         right fasciculus gracilis, you still have crude touch
         from the right lower extremity because the left ALS
         is fine and dandy!!! 
         
           We know that the central processes of delta
         and C fibers ASCEND approximately 2 levels before
         they synapse in the dorsal horn. In other words, dorsal
         horn cells which send their axons across into the
         anterolateral system receive their pain and temperature
         information from TWO spinal segments below. Thus,
         instead of the gross approximation of deficits of pain and
         temperature below the level of the lesion on the
         contralateral side, it is best to say the deficits start two
         levels below the lesion of the ALS and includes everything
         below this level. Of course, the deficits are contralateral.
         For example, a lesion of the ALS at T1
         will result in deficits in pain, temperature, and crude
         touch from T3 (2 segments below) and below on the
         contralateral side of the body.
      
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